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ACRP Certified Professional Sample Questions:

1. A Phase I drug trial has been completed and preparations are being made to proceed to a Phase II trial. Who is responsible for revising the IB with this updated information?

A) Health authority
B) Sponsor
C) Investigator
D) DSMB/IDMC


2. All of the following are steps to assure an effective risk management approach while conducting a clinical study EXCEPT:

A) Identifying potential study risks.
B) Assessing risk based on study impact.
C) Documenting all possible risk scenarios.
D) Controlling risk by setting thresholds of risk acceptability.


3. When designing a clinical trial, why is it important to define the study population?

A) To determine the study objectives
B) To determine where to conduct the study
C) To support subject recruitment to the study
D) To support the study objectives


4. The PI did not record the relationship to IP in the medical chart when assessing an adverse event. The CRC noticed the omission and brought it to the PI's attention. How should this be addressed?

A) The PI should notify the monitor.
B) The CRC should write a note to file.
C) The CRC should amend the medical chart.
D) The PI should amend the medical chart.


5. An impartial witness should be present during the entire informed consent discussion when:

A) A parent/guardian is consenting for a minor subject.
B) An interpreter is translating the consent form for a subject.
C) A legally acceptable representative is unable to read.
D) A subject has been determined to be vulnerable.


Solutions:

Question # 1
Answer: B
Question # 2
Answer: C
Question # 3
Answer: D
Question # 4
Answer: D
Question # 5
Answer: C

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